Endocrine Abstracts

Background-Aim: Urolithiasis is a frequent and recurrent pathology. Diabetes has a very important role in the formation of kidney stones. The objective of our study was to study the influence of age on the morpho-constitutional characteristics of urolithiasis in diabetic patients in southern Tunisia.Methods: This is a mono-centric retrospective and descriptive study of urinary lithiasis cases in diabetic patients. The lithiasis were identified by the mor...

Introduction: Melatonin is involved in many physiological processes, including the regulation of circadian rhythms, sleep, antioxidant effect, aging, tumor growth, reproduction and bone formation. The latter function is also regulated by the metabolism of vitamin D. Our goal during this study is to detect a possible increase in vitamin D levels under the effect of exogenous melatonin.Participants and methods: Different anthropometric parameters were coll...

The present study aimed to investigate the effect of time-of-days (TOD) on some biochemical and hormonal responses after resistance training sessions.Methods: Ten trained subjects performed three resistance-training-sessions at 0700 h, 1300 h and 1700 h. Each training-session included six upper and lower body resistance exercises with 3×10 repetitions. Blood lactate (Lac), creatine kinase (CK), lactate dehydrogenase (LDH), cortisol (C) and testoster...

Introduction: Cortisol level measurement is required in the diagnosis and management of adrenal, pituitary and hypothalamic pathologies.Aim: The aim of this study was to evaluate clinician’s practice in ordering cortisol test.Methods: A retrospective study concerning 63 cortisol requests data collected by the laboratory computer system (Health Lab) between January 2024 and February 2024. Only requests of 0800 hours plasma cort...

Introduction: Allgrove syndrome or Triple A (3A) syndrome is a rare autosomal recessive disease characterized by alacrima, esophageal achalasia and adrenocorticotropic hormone-resistant adrenal insufficiency.Observation: A 3-year-old and 9 months patient, from a consanguineous marriage, consulted for melanoderma, with family history: sisters with an heterozygous mutation of the AAAS gene, two paternal cousins, 5 years and 22 years, followed for autism an...

Introduction: Early diagnosis is therefore important for patients with asymptomatic diabetes mellitus. The aim of this study is to validate the use of Urine Dipstick in the screening of glycosuria (Gu).Material and methods: Our study involved 30 fresh urine specimens. Urinalysis was performed by dipstick (SPINREAT®). Gu was measured by the hexokinase method (DxC800® Beckman Coulter). The gold standard to diagnose Gu was co...

Introduction: Inappropriate laboratory test utilization can result in unnecessary patient testing and increased healthcare costs. Thyroid-stimulating hormone (TSH) is recommended as the first-line test for investigating and monitoring thyroid dysfunction. We evaluate Thyroid function tests (TFTs) ordering in our hospital practice.Methods: A retrospective descriptive study included 400 TFTs requests. TFTs of interest were: TSH and FT4. These tests request...

Background/Aim: Since diabetes is the most common endocrine disorder and the diabetic ketoacidosis (DKA) is considered as a medical emergency, our aim was to determinate the frequency of symptoms and precipitating factors of DKA in type 1 and type 2 diabetesMethods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 to December 2022. We compared the di...

Background/Aim: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Our aim was to study the clinical features of DKA and precipitating factors responsible for DKA in diabetic patients.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 and December 2021. Initial kalemia levels (k +) on presentation were determinat...

Introduction: Diabetic ketoacidosis (DKA) is an extreme metabolic state caused by insulin deficiency. Hypophosphatemia in DKA often occurs during hospitalization. The aim of this study was to determine the prevalence and determinants of hypophosphatemia during the treatment of diabetic ketoacidosis.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between Octobe...